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Hotel Sempione, unique in style and personality

Hotel Sempione, restyled in December 2013, is located in a privileged position in the heart of the historical center of Florence, just 200 meters from Santa Maria Novella train station and from Firenze Fiera Congress & Exhibition Center (Palazzo dei Congressi, Fortezza da Basso e Palazzo degli Affari). The Duomo, the main Florentine museums (Uffizi Gallery and Accademia Gallery) and the major shopping districts are all just a stone-throw away from our hotel.

The Sempione offers each guest a unique experience of freshly redesigned hotel by its new owners Serena and Michele, who gave it a breath of new life in a chic and elegant, yet informal style.


  1. The best available price
    You will always find the best available price on our official website!
  2. Your credit card details are safe with us
    Our booking online system guarantees the best protection. You can use your credit card without any worries!
  3. Exclusive Special Offers
    Take advantage of our exclusive special offers, available only on our official website!
  4. Reservations easy to modify or cancel
    Your reservations can be modified or cancelled much more easily when booking directly with us
  5. Direct Contact
    Our STAFF will be at your service even before your arrival!